To access the web portal, one should connect to http://localhost/cgi-bin/mobyle/portal.py Release 1.0.4 introduce a possible break in previous xml description. For more info: https://projets.pasteur.fr/repositories/entry/mobyle/tags/release_1_0_4/UPDATE?rev=3969 Release 1.0.6 requires a mobyle-programs update to version 4.0. Those programs files are incompatible, and user XML files may need an update on issimple attribute usage (see UPDATE). To upgrade, remove package mobyle-programs, upgrade mobyle, then install mobyle-programs.