Orthanc-WSI brings support of whole-slide imaging for digital pathology into Orthanc, the lightweight, RESTful Vendor Neutral Archive for medical imaging. It is made of 3 components: (a) A command-line tool called "OrthancWSIDicomizer" that converts whole-slide images to DICOM. OpenSlide can be used to decode proprietary file formats. (b) An Orthanc plugin to display such DICOM images in a standard Web browser thanks to OpenLayers. (c) A command-line tool called "OrthancWSIDicomToTiff" that allows one to create a standard hierarchical TIFF file from some DICOM whole-slide image stored in Orthanc. Homepage: https://orthanc.uclouvain.be/book/plugins/wsi.html